Table 3. Results of multivariate Cox proportional-hazards regression analysis of factors correlated with OS in Swedish patients diagnosed with RCC between 2000 and 2008.
| RCC model (n=8009) | ||
|---|---|---|
| |
HR (95% CI) |
P
value |
| Gender (female vs male) |
0.897 (0.842–0.954) |
0.001 |
| Age |
1.004 (1.001–1.006) |
0.008 |
| Nephrectomy (yes vs no) |
0.152 (0.142–0.162) |
<0.001 |
| Institution size (largea
vs small) |
1.047 (0.981–1.117) |
0.165 |
| Year of diagnosis (2006–2008 vs 2000–2005) |
0.714 (0.664–0.767) |
<0.001 |
|
Region of Sweden (region of interest vs West) | ||
| South | 0.893 (0.808–0.988) | 0.028 |
| Mid/central | 0.989 (0.899–1.088) | 0.825 |
| Stockholm | 0.871 (0.786–0.965) | 0.009 |
| East | 0.895 (0.802–0.999) | 0.048 |
| North | 1.049 (0.936–1.176) | 0.409 |
Abbreviations: CI=confidence interval; HR=hazard ratio; OS=overall survival; RCC=renal cell carcinoma. Note: for continuous variables (e.g., age), an HR>1 equates to risk reduction when the value decreases and an HR<1 equates to isk reduction when the value increases; for binary variables, an HR<1 equates to risk reduction for the first category and an HR>1 equates to risk reduction for the second category.
a
A large institution indicates a university urology clinic, where patients were diagnosed, and does not include university oncology clinics.