Table 2. Association between EpCAM expression and clinicopathological parameters.
| Clinicopathological parameter | EpCAM-positive | EpCAM-negative | P value | ||
|---|---|---|---|---|---|
| Mean tumour size (mm) |
34.2 |
27.8 |
<0.0001 |
||
| Mean age age at diagnosis (years) |
63.7 |
63.3 |
0.6220 |
||
|
Tumour stage |
|
|
|
|
<0.0001 |
| pT1 |
132 |
36.3 |
232 |
63.7 |
|
| pT2 |
366 |
50.3 |
362 |
49.7 |
|
| pT3 |
65 |
62.5 |
39 |
37.5 |
|
| pT4 |
97 |
57.4 |
72 |
42.6 |
|
|
Lymph node involvement |
|
|
|
|
0.0023 |
| pN0 |
329 |
46.9 |
372 |
53.1 |
|
| pN1 |
248 |
46.9 |
281 |
53.1 |
|
| pN2 |
83 |
62.9 |
49 |
37.1 |
|
|
Tumour grade |
|
|
|
|
<0.0001 |
| 1 |
99 |
31.1 |
219 |
68.9 |
|
| 2 |
234 |
42.5 |
317 |
57.5 |
|
| 3 |
327 |
65.9 |
169 |
34.1 |
|
|
Oestrogen receptor |
|
|
|
|
<0.0001 |
| ER+ |
439 |
42.9 |
583 |
57.1 |
|
| ER− |
221 |
65.2 |
118 |
34.8 |
|
|
HER2 |
|
|
|
|
0.0298 |
| HER2+ |
144 |
54.3 |
121 |
45.7 |
|
| HER2− |
516 |
46.9 |
584 |
53.1 |
|
|
Ki67 |
|
|
|
|
<0.0001 |
| Ki67+ |
593 |
55.4 |
477 |
44.6 |
|
| Ki67− | 66 | 23.0 | 221 | 77.0 | |
Abbreviations: EpCAM=epithelial cell adhesion molecule; ER=oestrogen receptor; HER2=human epidermal growth factor receptor 2; PR=progesterone receptor.