Table 4. Association between EpCAM expression and breast cancer intrinsic subtype.
|
EpCAM-positive |
EpCAM-negative |
P-value |
|||
|---|---|---|---|---|---|
| Intrinsic subtype | n | % | n | % | <0.0001 |
| Luminal A (ER+ and/or PR+, HER2−, Ki-67<14%) |
48 |
22.5 |
165 |
77.5 |
|
| Luminal B (HER2-negative) (ER+ and/or PR+, HER2−, Ki-67⩾14%) |
332 |
49.3 |
341 |
50.7 |
|
| Luminal B (HER2-positive) (ER+ and/or PR+, HER2+) |
63 |
40.9 |
91 |
59.1 |
|
| HER2 type (ER−, PR−, HER2+) |
81 |
73.0 |
30 |
27.0 |
|
| Basal-like (ER−, PR−, HER2−) | 136 | 63.8 | 77 | 36.2 | |
Abbreviations: EpCAM=epithelial cell adhesion molecule; ER=oestrogen receptor; HER2=human epidermal growth factor receptor 2; PR=progesterone receptor.