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(A) HIVvir+ (n=17) and HIVavir+ (n=17) individuals exhibit significant differences in Breg frequency compared with HIV− individuals (n=19) (B) yet comparable B cell frequencies. (C) Despite low frequency, the Bregs of HIVavir+ individuals (n=9) exhibited a higher frequency of IL-10-positive cells than Bregs from healthy controls (n=10). P values (two-tailed t-test; confidence interval of 95%) are indicated.
