Figure 2. Selk^−/− leads to decreased foam cell formation.

BMDMs from WT or Selk^−/− mice were treated with TNF-α for 4 h, followed by incubation with AcLDL for 24 or 48 h. Levels of ingested AcLDL were determined by fluorescent microscopic evaluation of Oil Red O. Representative images are shown for lipid content at 48 h. Data represent mean ± se (n=3). *P < 0.05.