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. 2013 May;93(5):751–759. doi: 10.1189/jlb.0912473

Figure 1. Increased anti-GPI serum transfer-induced arthritis in Tlr2−/− mice.

Figure 1.

(A) Tlr2−/− and WT mice were subjected to serum transfer-induced arthritis by i.p. administration of 100 μl K/BxN anti-GPI serum. The course of the arthritis was determined by the clinical activity score (maximum 12) and (B) the change of ankle swelling (Δ) in millimeters of the two hind ankles (ankle thickness). Data represent five independent experiments, presented as the mean ± se of 31 WT and 37 Tlr2−/− mice on Days 0–7 and 24 mice in each group on Day 9. *P < 0.05; **P < 0.01; ***P < 0.001 between the Tlr2−/− and WT mice on the indicated days.