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Identification of a candidate sphingolipid synthase from Toxoplasma gondii (TgSLS). Protein sequence alignment of D1, D2, D3 and D4 from HsSMS1 and 2, PfSMS1 and 2 and TgSLS. The positions highlighted in black are fully conserved; those in dark grey show conservation of strongly similar groups; those in light grey show conservation of weakly similar groups. The 3 residues of the predicted catalytic triad within D3 and D4 are designated by *.
