Table 5.
Multivariate Cox proportional hazard model evaluating predictors for disease progression and the necessity of repeated WLL
| Variable | Hazard ratio* | CI 95% | p value | |
|---|---|---|---|---|
|
Disease progression
|
|
|
|
|
|
KL-6, U/mL (cont.) |
0.999 |
0.998 |
1.000 |
0.090 |
|
KL-6 ≥1526, U/mL (binary) |
3.844 |
0.460 |
288.120 |
0.046 |
| Gender (female=1) (binary) |
18.030 |
2.378 |
136.696 |
0.051 |
|
Necessity of repeated WLL
|
|
|
|
|
|
KL-6, U/mL (cont.) |
1.000 |
1.000 |
1.001 |
0.196 |
| PaO2, mmHg (cont.) |
0.897 |
0.579 |
0.969 |
0.028 |
|
KL-6 ≥2157, U/mL (binary) |
9.408 |
0.794 |
111.511 |
0.008 |
| PaO2, mmHg (cont.) |
0.97 |
0.93 |
1.00 |
0.038 |
| LDH, IU/L (cont) | 46.449 | 1.661 | 1299,262 | 0.024 |
Definition of abbreviation: CI; confidence interval.
* Calculated by stepwise conditional LR method. All significant predicting factors in the univariate analysis were included in the multivariate model. Only the factors that influence the model (adjusting factors) are reported in the Table.