TABLE 3.
Time to Unreliability of the Antibiogram for Pseudomonas aeruginosa Isolates Based on Location of Isolation
| Antibiotic | Overall day (95% CI) | Non-ICU hospital ward day (95% CI) | ICU day (95% CI) | P a |
|---|---|---|---|---|
| Amikacin | 28 (21–>30) | 24 (<1–>30) | >30 (<1–>30) | .69 |
| Ceftazidime | 10 (8–11) | 12 (7–21) | 5 (<1–8) | .003 |
| Ciprofloxacin | 15 (9–19) | 19 (13–22) | 10 (<1–>8) | .66 |
| Gentamicin | 21 (12–27) | 21 (12–29) | 22 (<1–130) | .26 |
| Imipenem-cilastin | 10 (8–14) | >30 (13–>30) | 2 (<1–8) | <.0001 |
| Piperacillin-tazobactam | 10 (7–13) | 11 (2–>30) | 5 (<1–10) | .07 |
| Tobramycin | 9 (5–14) | 13 (1–>30) | 1 (<1–8) | .03 |
NOTE. CI, confidence interval; ICU, intensive care unit.
a
Comparison of time to unreliability of the antibiogram for isolates obtained in the ICU vs non-ICU hospital wards.