Video 5. Spatiotemporal demonstration of 365 days of simulated shedding with noninfectious cell-free particles.
The left panel represents total cell-free HSV DNA copies per milliliter present over time. The right panel represents spatial spread of virus during the episode; each hexagon contains one region of shedding. Amount of virus within a single region is displayed according to a heat map adjacent to the spatial map. The simulation is notable for lack of prolonged episodes and lack of episode re-expansion.
elife00288v005.f4v (3.5MB, f4v)
DOI: 10.7554/eLife.00288.030