Fig. 4.

Effect of MJ33 on the proliferation of cells in culture. (A) Proliferation of A549 cells during exposure to 0, 10, or 25 µM MJ33 during a 10-day incubation. (B) Clonogenic assay of A549 cells after a 2- or 7-day exposure to MJ33 at 0–25 µM. At the end of exposure, the number of colonies were counted and expressed as a fraction of the number of cells that were originally plated. (C) Clonogenic assay of mPMVECs treated with 0–25 µM MJ33 for 1, 2, or 7 days. Cells were studied during the exponential growth phase or at confluence (confl-24h). Mean ± S.E. for n = 3–4.