TABLE 1.

Lung uptake of MJ33 at increasing time after i.v. or i.t. injection as determined by MS

Data are presented as mean ± range for n = 2; all other values are single measurements. The amount of MJ33 was calculated based on the area ratios (Fig. 2) using a calibration curve constructed with the same amount of internal standard and variable amount of MJ33.

Time Postinjection	Amount Injected	Uptake %, of Injected Dose
		i.t.	i.v.
h	nmol	%
4	0.4	68 ± 4	23 ± 2
	4	87	42
	10	67	33
24	0.4	35	20
	4	51	32
	10	55	31
48	10	46	40
72	0.4	nd	nd
	4	nd	nd
	10	nd	nd

nd, none detected.