Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Association of UGT1A-3′UTR single nucleotide polymorphism genotype with ratios of exon 5a mRNA to exon 5b mRNA splice variant content measured in 40 human liver bank samples
| Exon 5a/Exon 5b mRNA Ratio |
|||||
|---|---|---|---|---|---|
| UGT1A Genotype | n | Mean | S.D. | P Value* | |
| rs10929303 | C/C | 27 | 1.5 | 3.1 | *0.015 |
| C/T | 10 | 7.7 | 9.4 | ||
| T/T | 3 | 11.0 | 10.8 | ||
| rs1042640 | C/C | 26 | 1.5 | 3.2 | *0.012 |
| C/G | 12 | 6.5 | 8.9 | ||
| G/G | 2 | 15.9 | 9.5 | ||
| rs8330 | C/C | 24 | 1.0 | 1.6 | *0.008 |
| C/G | 13 | 7.1 | 8.9 | ||
| G/G | 3 | 11.0 | 10.8 | ||
P < 0.05 for analysis of variance on log-transformed data.
