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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Feb 7;33(4):737–743. doi: 10.1161/ATVBAHA.112.300386

Figure 2. TXNIP is required for activation of VEGFR2 and PLCγ1 in EC.

Figure 2

(A) HUVEC were transfected with control siRNA or TXNIP siRNA. After 48 hrs, the cells were treated with VEGF (10 ng/ml) for the indicated times. Cell lysates were immunoblotted with p-VEGFR2 (Y1175), VEGFR2, p-PLCγ1 (Y783), and PLCγ1. (B-C) Lower panels are quantification analysis. *P<0.05 vs. control siRNA+VEGF (mean ± SD; n=3).