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. Author manuscript; available in PMC: 2013 Apr 18.
Published in final edited form as: Dev Biol. 2008 Apr 15;320(1):19–29. doi: 10.1016/j.ydbio.2008.03.045

Fig. 4.

Fig. 4

Tooth initiation is unaffected in Wnt1-Cre;Tgfbr2 fl/fl conditional knockout mice. (A–D) HE staining of sections of incisor (A, B) and molar (C, D) tooth germs from wild-type and Wnt1-Cre;Tgfbr2fl/fl E12.5 embryos. (E–J) Whole mount in situ hybridization of wild-type and Wnt1-Cre;Tgfbr2fl/fl maxilla (E, G, I) and mandible (F, H, J) processes. Shh expression at E11.5 (E, F), Lef1 expression at E12.5 (G, H), and Bmp2 expression at E12.5 (I, J) are unaffected in the Wnt1-Cre;Tgfbr2fl/fl embryos. Arrows indicate locations of tooth germs. Arrowheads indicate the location of expression. Tooth germs are outlined with dotted lines. Scale bar in panel A=50 μm. Scale bar in panel E=2 mm.