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. Author manuscript; available in PMC: 2013 Apr 18.
Published in final edited form as: Dev Biol. 2008 Apr 15;320(1):19–29. doi: 10.1016/j.ydbio.2008.03.045

Fig. 8.

Fig. 8

Altered expression of genes involved in tooth initiation in Wnt1-Cre;Alk5fl/fl mice. Whole mount in situ hybridization analysis of tooth initiation related genes in wild-type and Wnt1-Cre; Alk5fl/fl conditional knockout (CKO) embryos. (A, B) Bmp4 at E10.5. (C, D) Fgf8 at E10.5. (E, F) Pitx2 at E11.5. (G, H) Islet1 at E10.5. (I, J) Bmp4 at E12.5. Inserts show the differential expression of Bmp4 in the epithelium and mesenchyme from the same embryo. (K, L) Pax9 at E10.5. (M, N) Msx1 at E10.5. (O, P) Msx2 at E10.5. (Q, R) Barx1 at E10.5. Arrowheads highlight location of expression. Scale bar in panel A=2 mm.