Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Apr 11;8(4):e61933. doi: 10.1371/journal.pone.0061933

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Maes et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Panel A shows the influence of coefficient of variation on sample size, assuming a power of 0,8 and a fold change of 1,5. The higher the variation in a setup, the more replicates are needed to obtain the same power. Panel B illustrates power versus number of replicates when detecting various fold changes with following parameters: CV = 30% and a significance level of 0,05. The more subtile changes one wants to observe, the more replicates are required (B).