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The cytotoxic activity of compounds against three human cancer cell lines.a
| IC50 (nM) ± Standard deviation | |||
|---|---|---|---|
|
| |||
| Compounds | MCF-7 | OVCAR 8 | NCI/ADR-RES |
| 1 | 4.0 ± 0.5 | 20 ± 0 | 25 ± 7 |
| 39 | 200 ± 0 | 250 ± 70 | 750 ± 200 |
| 40 | 430 ± 200 | 300 ± 0 | 750 ± 400 |
| Paclitaxel | 2.0 ± 0 | 7.5 ± 2 | >5,000 |
A standard deviation of 0 indicates the same value was obtained in all experiments (usually two independent determinations)
