Table 3.

Modulation of the immune parameters in the MSC-kidney transplantation recipients

No	Age/Sex	Clinical outcome at 12 Month	Tregs1	Donor-specific lymphocyte proliferation2	Donor-specific T cell proliferation3	Cytokines4
1	34/M	Borderline change	↑↑	↑	-	IL-10 at D + 7 IL-6 at D + 7
2	48/F	No AR	↑↑	-	-	IL-10 at D + 30
3	40/M	No AR	-	ND*	ND*	NC**
4	32/F	ACR	-	↑	↑↑	NC**
5	36/M	No AR	-	↓↓	↓↓	IL-6 at D + 7 IFN-γ at D + 30
6	36/F	Borderline change	-	-	-
7	40/F	ACR	-	↓	↓↓	IFN-γ at D + 4

¹Represented by the level of FoxP3mRNA : compared to baseline (D −35) control (Figure 1).

²Peripheral blood lymphocytes were co-cultured with donor cells (MLR) (Figure 2).

³ConA-induced T cell proliferation in the MLR system. (Figure 3).

⁴Cytokines their secretion was significantly increased compared to donor and baseline (D-35) level. (Figures 4, 5, 6).

*ND = Not detected: due to the lack of sample.

**NC = No changes.

↑ or ↓ = Increased or decreased values compared to baseline (D-35) control.