Table 1. Summary of inactivating mutations in cetacean SWS1 and LWS genes.

SWS1 Mutations
Taxon	Number of Exon or Intron	Inactivating Mutation Including Alignment Number and Nucleotide Position(s)	Location on Tree (Ancestral Node Number: Descendant Node Number)
Tursiops truncatus	Exon 1	1-bp frameshift deletion (Alignment1:34)	49∶24
Mysticeti, Mesoplodon bidens, Platanista minor, Phocoenoides dalli (polymorphic), Delphinapterus leucas (polymorphic)	Exon 1	4-bp frameshift deletion (Alignment1:270–273)	27∶28, 41∶13, 37∶12, 47∶20, 45∶22
Physeter macrocephalus	Exon 1	1-bp frameshift insertion (Alignment1:310)	36∶10
Globicephala melas	Exon 1	50-bp frameshift deletion (Alignment1:261–311)	48∶25
Pontoporia blainvillei	Exon 1	2-bp frameshift deletion (Alignment1:308–309)	43∶17
Odontoceti	Exon 1	E113G amino acid replacement at the Schiff's base counterion site (bovine rhodopsin numbering) (Alignment1:338–340)	27∶35
Berardius bairdii	Intron 1	GT to GC splice site mutation (Alignment1:363–364)	39∶16
Eschrichtius robustus	Exon 2	8-bp frameshift deletion (Alignment1:808–815)	33∶6
Globicephala melas	Exon 3	4-bp frameshift insertion (Alignment1:1438–1441)	48∶25
Caperea marginata	Intron 3	GT to GC splice site mutation (Alignment1:1489–1490)	30∶4
Platanista minor	Exon 4	1-bp frameshift insertion (Alignment1:2201)	37∶12
Kogia breviceps	Exon 4	1-bp frameshift deletion (Alignment1:2336)	36∶11
Pontoporia blainvillei	Exon 4	2-bp frameshift insertion (Alignment1:2337–2338)	43∶17
Physeteroidea	Intron 4	GT to GA splice site mutation (Alignment1:2382–2383)	35∶36
Tursiops truncatus	Exon 5	1-bp deletion (Alignment1:4079)	49∶24
Balaenoptera acutorostrata	Exon 5	2-bp frameshift deletion (Alignment1:4103–4104)	31∶9

Inactivating mutations include frameshifts, Schiff's base counterion site mutations, and splice site mutations. All alignments are provided in Text S3. Inactivating mutations are also cross-referenced to branches in Figure 1.