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. 2013 Apr 18;9(4):e1003452. doi: 10.1371/journal.pgen.1003452

Figure 4. Eph function is not required for appropriate targeting of OSNs and uniglomerular PNs.

Figure 4

(A–B) OSN terminals innervating glomerulus VA1l/m appear comparable to (A) controls in (B) Eph null animals. (C–F) α-sNPF (green) labels specific sets of OSN terminals including (C) DA1 and (E) DL3 in the adult antennal lobe of control animals. α-sNPF immunoreactivity appears comparable to controls in the (D) DA1 and (F) DL3 of Eph null mutants. α-Brp (red) labels the neuropil. (G–H) Targeted expression of Eph in the olfactory sensory neurons does not change their overall pattern and OSNs appear comparable to (G) controls. (I–J) Uniglomerular projection neurons appear normal in Eph null animals. (I) Innervation pattern of projection neurons innervating glomeruli VA1d and DA1 in Mz19mCD8::GFP animals is unchanged in (J) in Eph null mutants (Mz19mCD8::GFP; EphX652).