Table 6. Comparison of patients from Sri Lanka that tested positive only by the multiplex rRT-PCR and those that tested positive by both the multiplex rRT-PCR and reference assays.
| Multiplex rRT-PCR Positive | Multiplex rRT-PCR Positive | ||
| Reference Method Negative | Reference Method Positive | p-value | |
| Patients, n (%) | 22 (55) | 16 (40) | ND |
| Age, mean (SD) | 7.1 (3.6) | 6.1 (4.0) | 0.43 |
| Day of Illness, mean (SD) | 5.8 (1.6) | 6.1 (1.2) | 0.53 |
| IgM Positive, n (%) | 19 (86) | 16 (100) | 0.25 |
| Primary Dengue, n (%) | 7 (32) | 11 (69) | 0.047 |
| Illness Severity, n (%) | |||
| DF | 15 (68) | 6 (38) | 0.10 |
| DHF/DSS | 7 (32) | 10 (62) | |
| Any ICU Care, n (%) | 4 (18) | 7 (44) | 0.15 |
| Viral Load, mean (SD)* | 2.98 (0.61) | 4.4 (1.41) | 0.0002 |
*
Viral Load expressed as log10 cDNA equivalents/mL of patient plasma.
ND, not determined; SD, standard deviation.