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. 2013 Apr 18;8(4):e61923. doi: 10.1371/journal.pone.0061923

Figure 1. PAR2 mediates blood flow restoration in a hind limb ischemia model.

Figure 1

The average blood perfusion ratio between ischemic and non-ischemic hind limbs was measured with laser Doppler before, directly after ligation, at day 3 and every week in a period of four weeks. Representative images of laser Doppler measurements of the ligated hind limbs are shown. (A) The ratio measured in PAR1-/- mice (n = 10) compared to the ratio measured in WT mice (n = 9). (B) The blood perfusion in PAR2-/- mice (n = 7) was compared to the ratio measured in WT mice (n = 10). * p<0.05, ** p<0.01, *** p<0.001.