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. 2013 Apr 18;8(4):e61923. doi: 10.1371/journal.pone.0061923

Figure 4. PAR2 contributes to the differentiation of circulating monocytes after femoral artery ligation.

Figure 4

Before (b, white circles) and seven days after ligation (a, grey circles), blood was drawn from WT, PAR1-/- and PAR2-/- mice to perform FACS analysis. (A) Absolute number of peripheral blood (PB) monocytes. Monocytes were gated to analyse the change in levels of (B) repair-associated Ly6C-low monocytes and (C) pro-inflammatory Ly6C-high monocytes upon ischemia, which is indicated in percentage of total monocytes. (D) Change in ratio of Ly6C-high/low monocytes upon ligation. # p<0.1, * p<0.05, ** p<0.01.