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. 2013 Apr 18;8(4):e60888. doi: 10.1371/journal.pone.0060888

Figure 6. Disruption of Drosha in VSMCs attenuates ERK1/2 and AKT in vitro and in vivo.

Figure 6

A. Phospho and total ERK1/2 and AKT were detected by Western blot in umbilical arteries pooled from embryos of Drosha cKOs and WT controls at E12.5 (n = 6). B. The expression of phospho and total ERK1/2 and AKT in knockout and control VSMCs were detected by western blot. Protein band intensity was quantified using densitometry and normalized to GAPDH. (*p<0.05,**P<0.01,***P<0.001). C. The expression of phospho and total ERK1/2 and AKT in KD and control VSMCs was detected by Western blot. Error bars indicate the SD (**P<0.01).