Table 4. The Rate of Decline in FEV1 According to Serum Myeloperoxidase LevelsOver 11 Years in LHS.

	Serum Myeloperoxidase Levels
	Quint1	Quint2	Quint3	Quint4	Quint5	P for trend
Annual Decline in FEV1 from year 0 to year 11 (ml/yr, mean±SD)	44±33	44±34	49±33	52±33	52±35	<.0001
Annual Decline in FEV1 from year 0 to year 11 (% of baseline FEV1 mean±SD)	16.8±12.4	16.9±13.0	18.2±12.3	19.3±13.4	19.2±13.2	<.0001
Annual Decline in FEV1 from year 0 to year 11 (% of predicted per year, mean±SD)	0.74±1.03	0.76±1.07	0.89±1.03	0.93±1.09	0.94±1.11	<.0001
Adjusted Relative Rate of Decline in ml/yr (mean±SE)	1 (reference)	−0.37±1.62	2.01±1.61	3.67±1.63	1.62±1.64	0.0479*

A positive number denotes faster decline in FEV1.

^*adjusted for age, sex, race, baseline FEV1, and smoking status at visit 5.