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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Dev Biol. 2013 Mar 6;377(1):67–78. doi: 10.1016/j.ydbio.2013.02.014

Figure 5. DMRT1 regulates distinct genes in testis and ovary, but regulates pluripotency in both.

Figure 5

(A) Heat map showing relative expression of 1192 mRNAs that differed more than twofold between B6 or 129Sv wild type and Dmrt1 mutant testes or wild type and Dmrt1 mutant 129Sv ovaries at E15.5. In each wild type versus mutant comparison transcripts were normalized to wild type. (B) Heat map showing mRNAs misexpressed both in testis and ovary. (C) qRT-PCR analysis confirming elevated mRNA expression of pluripotency regulators in mutant ovaries at E15.5. *P<0.05, and ***P<0.001, unpaired t-test, comparison of WT vs mutant.