Appendix C.
Adjusted odds ratio estimates by patient characteristics of receiving continuous antidepressant treatment through 84 and 180 days and completion of at least 3 in-person visits within the first 84 days of treatment initiation, n=15,343*
| 84 days continuous treatment | 180 days continuous treatment | 3+ in-person visits within first 84 days | |
|---|---|---|---|
|
| |||
| Adjusted OR (95% CI)** | |||
| BMI value (most recent) | |||
| 18.5 | 1.03 (0.96, 1.11) | 1.06 (0.99, 1.14) | 0.99 (0.91, 1.08) |
| 25 | 1 (referent) | 1 (referent) | 1 (referent) |
| 30 | 0.98 (0.94, 1.01) | 0.95 (0.92, 0.99) | 1.01 (0.96, 1.06) |
| 35 | 0.95 (0.91, 1.00) | 0.91 (0.87, 0.96) | 1.01 (0.94, 1.10) |
| 40 | 0.93 (0.86, 1.01) | 0.87 (0.81, 0.93) | 1.02 (0.90, 1.15) |
| 45 | 0.91 (0.77, 1.07) | 0.83 (0.71, 0.96) | 1.03 (0.83, 1.28) |
|
| |||
| BMI trajectory over last 9 mo. | |||
| Declining | 1.01 (0.92, 1.12) | 1.00 (0.92, 1.08) | 1.19 (1.04, 1.36) |
| Stable | 1 (referent) | 1 (referent) | 1 (referent) |
| Increasing | 1.03 (0.93, 1.14) | 1.03 (0.92, 1.14) | 0.92 (0.83, 1.03) |
| Unknown | 1.18 (1.08, 1.27) | 1.12 (1.04, 1.21) | 1.12 (1.02, 1.23) |
|
| |||
| Female | 0.87 (0.80, 0.94) | 0.89 (0.83, 0.95) | 0.91 (0.83, 1.00) |
|
| |||
| Age group | |||
| 18 to 25 | 0.90 (0.80, 1.01) | 0.99 (0.89, 1.10) | 1.00 (0.87, 1.14) |
| 26 to 35 | 0.98 (0.83, 1.15) | 0.99 (0.85, 1.16) | 1.20 (1.03, 1.41) |
| 36 to 45 | 0.86 (0.75, 0.99) | 0.88 (0.78, 0.99) | 1.08 (0.93, 1.25) |
| 46 to 55 | 0.85 (0.77, 0.94) | 0.92 (0.84, 1.01) | 1.07 (0.97, 1.19) |
| 56 to 65 | 1 (referent) | 1 (referent) | 1 (referent) |
|
| |||
| Current or former smoker | 0.70 (0.63, 0.77) | 0.75 (0.69, 0.82) | 0.70 (0.62, 0.79) |
|
| |||
| Anxiety at index | 1.00 (0.91, 1.09) | 0.87 (0.81, 0.93) | 0.98 (0.80, 1.20) |
|
| |||
| Sleep disorder at index | 1.23 (1.00, 1.50) | 1.04 (0.86, 1.26) | 0.80 (0.62, 1.03) |
*
Of 15,343 patients who contributed data to these analyses, 9,957 received continuous care through 84 days, 7,351 received continuous care through 180 days, and 2,775 had completed 3 or more visits within 84 days.
**
Odds ratio estimates are adjusted for sex, age group, BMI trajectory in the 9 months prior to index, smoking status, anxiety disorder, and sleep disorder, each measured at the beginning of the index treatment episode.
Abbreviations: OR=odds ratio; CI=confidence interval; BMI=body mass index