The Effect of Testosterone on Mood and Well-being in Men with Erectile Dysfunction in a Randomized, Placebo-Controlled Trial
| Table Baseline Demographics, Well-Being and Mood | ||
|---|---|---|
| Demographics |
Testosterone (n=70) |
Placebo (n=70) |
| Age (years) | 55.1 (8.3) | 54.6 (8.5) |
| Race – no. (%) | ||
| Black | 28 (41%) | 33 (47%) |
| White | 36 (53%) | 32 (46%) |
| Other | 4 (6%) | 5 (7%) |
| Body Mass Index (kg/m2) | 31.5 (6.4) | 32.7 (6.0) |
| Diabetes Mellitus – no. (%) | 13 (21%) | 14 (22%) |
| Hypertension – no. (%) | 29 (45%) | 27 (40%) |
| Cardiovascular Disease – no. (%) | 35 (50%) | 32 (46%) |
| Serum Testosterone | ||
| Total Testosterone (ng/dL) | 248 (62) | 254 (68) |
| Psychological General Well-Being Index Score (%) | ||
| Positive Well-being | 62 (17) | 61 (19) |
| Depressed Mood | 86 (14) | 83 (15) |
| General Health | 73 (16) | 73 (17) |
| Anxiety | 75 (15) | 72 (18) |
| Self Control | 85 (13) | 84 (14) |
| Global Score | 73 (12) | 72 (14) |
| Derogatis Affects Balance Scale Dimension | ||
| Joy | 13.0 (3.2) | 12.9 (4.3) |
| Contentment | 13.1 (2.9) | 12.8 (3.6) |
| Vigor | 12.2 (3.2) | 12.3 (4.1) |
| Affection | 14.4 (3.6) | 14.2 (3.8) |
| Depression | 3.9 (3.3) | 4.7 (3.7) |
| Anxiety | 5.4 (3.5) | 6.2 (3.1) |
| Guilt | 4.1 (3.7) | 4.4 (3.9) |
| Hostility | 4.5 (3.5) | 4.8 (3.7) |
Baseline characteristics are displayed as mean (standard deviation). Scores are reported prior to receipt of sildenafil, testosterone or placebo. Psychological General Well-Being Index scores may range from 0 to 100%, with higher scores reflecting improved well-being. Derogatis Affects Balance Scale dimension scores may range from 0 to 20, with higher scores reflecting greater affectivity of the respective dimension.