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. 2013 Mar 31;40(1):12–22. doi: 10.5653/cerm.2013.40.1.12

Figure 4.

Figure 4

Proliferation activity of HTR-8/SVneo cells and expression of the NET based on NE treatment. (A) The NET expression in HTR-8/SVneo cells after a 24-hour NE treatment. β-actin was used as an internal control. (B) The viability in HTR-8/SVneo cells after a 24-hour NE treatment. NE significantly induced an increase in cell proliferation. (C) The invasion activity of HTR-8/SVneo cells after NE treatment. (D) MMP-2 and MMP-9 activity in HTR-8/SVneo cell medium after 24-hour incubation with NE using zymography. The columns in the graph represent the intensity of MMP-2 and MMP-9 measured in triplicate. Significant difference are indicated by ap<0.05 vs. Mock. The values are expressed as the means±SE. M, mock control; MMP, matrix metalloproteinase; NE, norepinephrine; NET, norepinephrine transporter.