Table 1.
Patient characteristics.
| n | % | Overall survival | P | |
|---|---|---|---|---|
| Patient numbers (1990–2010) | 54 | |||
| Patient numbers (1990–2000/2001–2010) | 24/30 | 44/54 | ns | |
| Age (years) | 6.5 ± 4.2 | |||
| Age (<3/>3 years) | 14/40 | 26/74 | 42 ± 1/53 ± 1 | ns |
| Sex (male/female) | 32/22 | 59/41 | 54 ± 1/43 ± 1 | ns |
| Histology (classic/nodular/anaplastic) | 39/11/2 | 74/22/4 | 46 ± 1/68 ± 1/50 ± 3 | ns |
| Resection: CR/PR | 25/28 | 47/53 | 62 ± 1/40 ± 1 | 0.05 |
| Metastasis (no/yes) | 34/16 | 68/32 | 56 ± 1/30 ± 1 | 0.05 |
| Radiotherapy (yes/no) | 40/9 | 82/18 | 60 ± 1/11 ± 1 | 0.000* |
| Relapse (yes/no) | 18/31 | 37/63 | 13 ± 1/69 ± 1 | 0.001* |
| HDCT (yes/no) | 15/31 | 33/67 | 29 ± 1/57 ± 1 | ns |
| Status (CR/PR/dead) | 22/4/22 | 46/8/46 | ||
| Follow up (months) | 60.0 ± 2.6 | |||
| Survival (1990–2000/2001–2010) | 50 ± 7 (52 ± 1/40 ± 1) | ns |
Data are expressed as mean ± SEM. NS: no significance; CR: complete remission, PR: partial remission; HDCT: high dose chemotherapy and autologous stem cell rescue.*Significance at multivariate analysis.