Table 2.
Univariate association of comorbidity with moderate to severe pain at 2 and 5 years after primary TKA
| 2 years |
5 years |
|||||
|---|---|---|---|---|---|---|
| Variable | n/N (%) | Odds ratio (95% CI) | P-value | n/N (%) | Odds ratio (95% CI) | P-value |
| Heart disease (MI, CHF) | ||||||
| No | 465/6343 (7.3) | Reference | 292/3806 (7.7) | Reference | ||
| Yes | 40/535 (7.5) | 1.0 (0.7, 1.5) | 0.91 | 39/288 (13.5) | 1.9 (1.3, 2.8) | <0.01 |
| Peripheral vascular disease | ||||||
| No | 476/6521 (7.3) | Reference | 313/3914 (8) | Reference | ||
| Yes | 29/357 (8.1) | 1.1 (0.8, 1.7) | 0.56 | 18/180 (10) | 1.3 (0.7, 2.2) | 0.38 |
| Renal disease | ||||||
| No | 473/6495 (7.3) | Reference | 320/3925 (8.2) | Reference | ||
| Yes | 32/383 (8.4) | 1.2 (0.8, 1.7) | 0.47 | 11/169 (6.5) | 0.8 (0.4, 1.6) | 0.51 |
| Chronic obstructive pulmonary disease | ||||||
| No | 434/6140 (7.1) | Reference | 294/3698 (8) | Reference | ||
| Yes | 71/738 (9.6) | 1.4 (1.1, 1.8)* | 0.02 | 37/396 (9.3) | 1.2 (0.8, 1.7) | 0.36 |
| Diabetes (with or without organ damage) | ||||||
| No | 444/6225 (7.1) | Reference | 293/3750 (7.8) | Reference | ||
| Yes | 61/653 (9.3) | 1.3 (1.0, 1.8)* | 0.05 | 38/344 (11) | 1.5 (1.0, 2.2) | 0.06 |
| CTD | ||||||
| No | 468/6387 (7.3) | Reference | 301/3752 (8) | Reference | ||
| Yes | 37/491 (7.5) | 1.0 (0.7, 1.5) | 0.88 | 30/342 (8.8) | 1.1 (0.7, 1.7) | 0.65 |
| Depression | ||||||
| No | 430/6154 (7) | Reference | 286/3773 (7.6) | Reference | ||
| Yes | 75/727 (10.3) | 1.5 (1.2, 2.0)* | <0.01 | 45/321 (14) | 2.0 (1.4, 2.9)* | <0.01 |
| Anxiety | ||||||
| No | 456/6436 (7.1) | Reference | 295/3881 (7.6) | Reference | ||
| Yes | 49/445 (11) | 1.6 (1.2, 2.3)* | <0.01 | 36/213 (16.9) | 2.5 (1.6, 3.8)* | <0.01 |
*Significant values.