Table 1.
Cre−, flox/flox (n=4) | MHC-CKO (n=6) | |
---|---|---|
IDD, mm | 3±0.2 | 3±0.1 |
IDS, mm | 1.6±0.2 | 1.7±0.1 |
FS, % | 46.3±4 | 45±2.9 |
LV diastolic volume, μL | 28±4 | 28±3 |
LV systolic volume, μL | 5±2 | 5±1 |
EF, % | 83.7±4.8 | 82.6±2.6 |
AWTs, mm | 1.5±0.1 | 1.4±0.1 |
AWTd, mm | 0.9±0.1 | 0.9±0.1 |
PWTs, mm | 1.2±0.1 | 1.2±0.1 |
PWTd, mm | 0.9±0.1 | 0.9±0.1 |
HR, bpm | 525±9 | 462±37 |
Age, wk | 5 | 5 |
Weight, g | 20.3±0.6 | 21.0±0.4 |
P=NS for all of the above comparisons. IDD indicates intraventricular dimension in diastole; IDS, intraventricular dimension in systole; FS, fractional shortening; LV, left ventricle; AWTs, anterior wall thickness in systole; AWTd, anterior wall thickness in diastole; PWTs, posterior wall thickness in systole; PWTd, posterior wall thickness in diastole; and HR, heart rate.