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Autophagy is adaptive and essential under conditions of nutrient deprivation. A) Autophagy inhibition with bafilomycin decreased cell viability under SGF conditions. *P < 0.05. B) Autophagy inhibition with bafilomycin up-regulates ROS production under SGF conditions. **P < 0.01. C) Western blot for γH2AX showed that genotoxic stress under SGF conditions was augmented by the presence of autophagy inhibition with bafilomycin.
