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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Atherosclerosis. 2012 Oct 31;226(1):238–244. doi: 10.1016/j.atherosclerosis.2012.10.048

Table 3.

Association between HapE and carotid atherosclerosis

Variable IMT (μm)
P*
HapE noncarriers HapE carriers
No covariates
 Mean ± SD 742±108 701±94 0.007
 Median 725 687 0.03
 Minimum 565 555
 Maximum 1185 960
Multivariate analysis‡
 Model 1 (mean ± SE) 744±8 702±12 0.006
 Model 2 (mean ± SE) 748±9 701±12 0.002
 Model 3 (mean ± SE) 749±8 695±12 0.0007
‡

Model 1 adjusted for age; Model 2 additional adjusted for current smoking, alcohol consumption, physical activity, dietary intake of saturated fat and total caloric intake; Model 3 further adjusted for BMI, use of statins and Framingham score, which is a composite variable containing age, smoking, blood pressure, LDL, HDL and history of type 2 diabetes.

*

P values for differences between means were computed by GEE, and were adjusted for multiple testing by adjusted-FDR (q value). The p value for the difference in medians was calculated using the Kruskal-Wallis test.