Table 1.
Gross phenotypic and behavioural characteristics of adult WT and GluN3A KO mice using the SHIRPA primary screen
| Phenotype | WT mice | GluN3A KO mice | Phenotype | WT mice | GluN3A KO mice |
|---|---|---|---|---|---|
| Body position | 1 | 1 | Gait | 0 | 0 |
| Tremor | 0 | 0 | Tail elevation | 1 | 1 |
| Palpebral closure | 0 | 0 | Positional passivity | 2 | 2 |
| Coat appearance | 0 | 0 | Limb grasping | 1 | 1 |
| Whiskers | 0 | 0 | Corneal reflex | 0 | 0 |
| Defecation | 0 | 0 | Biting | 0 | 0 |
| Transfer arousal | 2 | 2 | Vocalization | 0 | 0 |
Each group: n = 5. For details on the scoring of each phenotype, please refer to the methods section. GluN3A, glutamate NMDA receptor subunit 3A; KO, knockout; WT, wild-type.