A, voltage ramps from −100 mV to +100 mV evoke an outward rectifying current in dTRPA1 that is potentiated at warm temperatures. B, dTRPA1 is activated by temperature in the range 20–35°C. Positive voltage shifts the temperature activation curve to the left (n = 11). C, current traces of dTRPA1 at indicated temperatures in response to the voltage protocol at the upper left. D, voltage-dependent activation of dTRPA1 at 24°C (n = 14), 28°C (n = 13) and 32°C (n = 8). Continuous lines are best fits to Boltzmann functions. Data are expressed as means ± SEM.