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. 2012 Oct 1;591(Pt 1):185–201. doi: 10.1113/jphysiol.2012.242842

Figure 2. Activation of HDH chimeric channels by heat and voltage.

Figure 2

A, schematic diagram of chimera construction. B, increasing temperature raises intracellular calcium concentration in HDH expressing cells. C, I–V curves of HDH channels. D, current traces of HDH chimeras at different temperatures in response to the voltage protocol indicated at the upper left. E, voltage-dependent activation of HDH at 16°C (n = 8), 20°C (n = 6) and 25°C (n = 7). dTRPA1, Drosophila transient receptor potential A1; hTRPA1, human TRPA1.