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. 2012 Oct 22;591(Pt 1):365–378. doi: 10.1113/jphysiol.2012.244350

Table 1.

Effects of group II and group III agonists on EPSCs in the three CF regions of the nucleus laminaris

In the presence of DCG-IV

CF region Control DCG-IV DCG-IV/Control Control l-AP4 l-AP4/Control
High Amplitude of 1st EPSC (nA) 2.25 ± 0.82 (6) 1.69 ± 0.69 (6)* 0.75 2.64 ± 0.62 (4) 2.28 ± 0.65 (4) 0.87
CV 0.09 ± 0.02 (6) 0.12 ± 0.02 (6) 1.31 0.08 ± 0.01 (4) 0.09 ± 0.01 (4) 1.05
PPR 0.89 ± 0.12 (3) 0.88 ± 0.09 (3) 0.98 0.58 ± 0.04 (4) 0.68 ± 0.03 (4) 1.16
Middle Amplitude of 1st EPSC (nA) 1.35 ± 0.46 (6) 0.75 ± 0.29 (6)* 0.56 2.48 ± 0.52 (4) 1.68 ± 0.43 (4)* 0.68
CV 0.11 ± 0.02 (5) 0.15 ± 0.03 (5)* 1.44 0.12 ± 0.05 (4) 0.18 ± 0.07 (4)* 1.57
PPR 0.55 ± 0.18 (3) 0.77 ± 0.18 (3)* 1.39 0.67 ± 0.16 (4) 0.90 ± 0.14 (4) 1.34
Low Amplitude of 1st EPSC (nA) 2.31 ± 0.44 (6) 0.91 ± 0.18 (6)† 0.39 2.01 ± 0.72 (5) 1.18 ± 0.48 (5)* 0.58
CV 0.09 ± 0.02 (6) 0.18 ± 0.03 (6)† 2.09 0.14 ± 0.03 (5) 0.20 ± 0.04 (5)* 1.49
PPR 0.70 ± 0.06 (6) 0.93 ± 0.05 (6)† 1.32 0.91 ± 0.10 (5) 1.24 ± 0.15 (5)* 1.37

The effect of l-AP4 was examined in the presence of DCG-IV. CF, characteristic frequency; CV, coefficient of variation; EPSC, excitatory postsynaptic current; PPR, paired pulse ratio. *P < 0.05; †P < 0.01. The number of cells is indicated in parentheses.