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. Author manuscript; available in PMC: 2013 Apr 19.
Published in final edited form as: Biol Chem. 2012 Jul;393(7):547–564. doi: 10.1515/hsz-2012-0119

Figure 2. EM for mitophagy.

Figure 2

Wild-type C57BL/6 mice were treated with acetaminophen (i.p., 500 mg/kg) for 6 h (A, B) or ethanol (gavage, 4.5 g/kg) for 6 h (C, D). Thin liver sections were processed for EM studies. (A and C) An early double-membraned autophagosome envelops mitochondria. (B and D) A late autolysosome contains degrading mitochondria.