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PEDF promotes RGC axon regeneration at 21 days after ONC. Representative GAP43+ immunohistochemistry after (A) cAMP-, (B) PEDF-, and (C) cAMP+PEDF-treatment (red arrow demarcates lesion site; scale bar: 200 μm). (D) High power image of boxed region in (C). (E) The mean number of axons present at different distances from the lesion center.
