Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ras-TKO ZEB1 shRNA-2 MEFs show a rate of proliferation similar to parent TKO Ras MEFs, whereas Ras-TKO ZEB1 shRNA-1 MEFs undergo rapid senescence. A, cell proliferation assay. Note also in Fig. 3B that Ras-TKO ZEB1 shRNA-2 MEFs are immortal. B and C, Ras-TKO ZEB1 shRNA-1 MEFs at day 4 stained for senescent β-galactosidase. Error bars, S.D. Scale bars, 20 μm.
