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. 2013 Feb 26;288(16):11024–11037. doi: 10.1074/jbc.M112.436006

FIGURE 7.

FIGURE 7.

MB also facilitates formation of disulfide-stabilized 4-R Tau compact monomer as well as intermolecular disulfides in 3-R Tau and 4-R Tau with a mutated cysteine. A, K18PL was incubated for 1 h at 37 °C in the absence (K18PL) or presence of CNDR-51348 (K18PL:51348) or MB (K18PL:MB). The samples were subsequently analyzed by SEC. B, 3-R Tau K19 was incubated for 1 h in the absence (K19) or presence of CNDR-51348 (K19:51348) or MB (K19:MB) followed by SEC analyses. C, K18PL containing the C291A mutation was incubated for 1 h at 37 °C in the absence (C291A) or presence of CNDR-51348 (C291A:51348) or MB (C291A:MB).