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Tau cysteine oxidation by ATPZ or MB is inhibited by cellular concentrations of GSH. K18 (A) or K19 (B) were incubated for 1 h at 37 °C in the absence (−) or presence of CNDR-51348 (51348), CNDR-51449 (51449) or MB or was pre-reduced (R) or pre-oxidized (O). These reactions were conducted either in the absence (−GSH) or presence (+GSH) of 5 mm GSH. The samples were then analyzed by native gel electrophoresis.
