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M. tuberculosis ctpC::hyg mutant accumulates Mn2+
| Metala | Whole cell metal content |
||
|---|---|---|---|
| Wild type | ctpC::hyg | Complemented | |
| pmol/mg protein | |||
| 7H9 medium | |||
| Manganese | 1.2 ± 0.3 | 2.1 ± 0.1b | 1.7 ± 0.1 |
| Zinc | 317 ± 12 | 283 ± 5 | 314 ± 23 |
| Copper | 28 ± 6 | 25 ± 1 | 28 ± 3 |
| Cobalt | 0.31 ± 0.04 | 0.23 ± 0.02 | 0.26 ± 0.06 |
| Iron | 237 ± 38 | 192 ± 7 | 455 ± 13 |
| 7H9 medium + Zn2+ | |||
| Zinc | 654 ± 18 | 581 ± 35 | 689 ± 28 |
a Cells were grown to log phase.
b Statistical significance at p < 0.037.
