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. 2011 Jul 26;3:87–99. doi: 10.2147/NSS.S12975

Table 1.

Summary of randomized studies directly comparing CBT to hypnotic medications

Study Treatment conditionsa N, mean age Results at posttreatment Follow-up period Results at follow-up
McClusky et al105 CBT vs TZ N = 30, mean age = 32 Self-report: CBT = TZ for improvements in SL and TST 9 weeks All participants maintained gains for SL and TST, CBT >TZ for improvements in SL
CBT = TZ for TST
Morin et al41 CBT vs TM vs PL N = 78, mean age = 65 Self-report: CBT, TM > PL for improvements in TWT, SE, WASO
PSG: CBT, TM > PL for improvements in WASO
24 months Only CBT participants maintained sleep gains for TWT, WASO, SE
Jacobs et al46 CBT vs ZP vs PL N = 63, mean age = 47 Self-report: CBT > ZP for improvements in SL, SE
CBT = ZP for improvements in TST
12 months Only CBT had f/u. All CBT gains maintained
Sivertsen et al45 CBT vs ZP vs PL N = 46, mean age = 62 Self-report: CBT = ZP for improvements in TWT and TST
PSG: CBT > ZP, PL for improvements in TWT CBT > PL for SE
6 months Self-report: CBT > ZP for improvements in TWT
PSG: CBT > ZP for improvements in TWT, SE
Wu et al106 CBT vs TM vs PL N = 71, mean age 38 Self-report and PSG: TM, CBT > PL for improvements in SL, SE, TST
TM > CBT for improvements in SL, SE, TST
8 months Self-report and PSG: CBT > TM for improvements in SL, SE, TST

Notes:

a

Because the purpose of this table was to show results of a direct comparison of CBT to hypnotics in a randomized study, treatment groups that combined CBT and hypnotic medication were not reported.

Abbreviations: CBT, cognitive behavioral therapy; PL, placebo; PSG, polysomnography; SL, sleep latency; SE, sleep efficiency; TM, temazepam; TST, total sleep time; TWT, total wake time; TZ, triazolam; WASO, wake after sleep onset; ZP, zoplicone.