Table 3.
Jackson C57BL/6 (n = 3) | IRF5+/+ 15G littermate (n = 4) | IRF5−/− 15G littermate (n = 3) | IRF5−/− 11G with DOCK2 mutation (n = 6) | |
---|---|---|---|---|
Total spleen cell number (×106) | 89.2±17.9 (100%) | 93.1±17.0 (100%) | 70.5±13.3 (100%) | 39.4±1.9 (100%) |
B cells (B220+) | 47.9±10.3 (53.6%) | 48.1±10.4 (51.7%) | 34.1±7.2 (48.3%) | 10.4±0.9 (26.4%) |
T cells (CD3+) | 29.2±6.3 (32.7%) | 30.0±2.9 (32.2%) | 25.2±4.0 (35.7%) | 17.4±1.0 (44.2%) |
Non-B and non-T cells (B220–CD3–) | 7.7±0.7 (8.6%) | 9.1±2.1 (9.8%) | 6.4±0.7 (9.1%) | 9.3±0.3 (23.6%) |