Figure 10.

Muscle phenotypes of wup A mutants. Electron micrographs of mutant somatic muscles. (A) Df(1)23437 embryo showing thin filaments with putative Z disk electrodense material at random locations along the filaments. (B) PL87 embryo with better organized parallel thin filaments and a lined up proto Z disk (arrow). (C) Adult indirect flight muscles with mutated Troponin I and Myosin heavy chain proteins (genotype: males wup A^hdp2; Mhc^D41/+). Note the nearly normal sarcomere, albeit some thin filaments bypass a Z disk and continue to the adjacent sarcomere (inset). (D) Detail of inset in C. (E) Detail of inset in D. (F) Adult indirect flight muscles with double mutant TnI (genotype: males wup A^hdp2 wup A^D3). Note the abnormal central part of some Z discs. Bar, 0.5 μm (A and D); 0.25 μm (B and E); 1 μm (C and F).