Table 1. Baseline characteristics of the study population by age quartiles.
| Age Quartiles | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |
| Age, years | 26 to 42 | 43 to 46 | 47 to 53 | 54 to 72 | Trend p |
| Baseline Information | |||||
| Gender (female), % | 44 (26.5%) | 28 (20%) | 52 (30.1%) | 40 (31%) | 0.146 |
| SBP, mmHg | 114.2±12.5 | 114.9±14.2 | 118.7±15 | 122.7±15.4 | <0.001 |
| DBP, mmHg | 72.9±9.6 | 74±10.2 | 75.5±9.8 | 76.3±9.2 | <0.001 |
| Pulse Pressure, mmHg | 0.87±0.07 | 0.88±0.07 | 0.89±0.06 | 0.89±0.07 | 0.005 |
| Pulse Rate, 1/min | 72.6±7.7 | 73.6±9.4 | 72.2±8 | 72.9±9 | 0.69 |
| Anthropometric Measures | |||||
| Body Height, cm | 167.4±7.3 | 168.3±7.4 | 165.4±7.8 | 164.6±8.7 | <0.001 |
| Body Weight, kgw | 66.5±12.4 | 68.1±9.9 | 66.2±10.8 | 65.7±11.4 | 0.31 |
| BMI, kg/m2 | 23.6±3.3 | 24±2.7 | 24.1±2.9 | 24.1±2.8 | 0.08 |
| Waist circumference, cm | 80.4±10.2 | 82.6±8.6 | 83±8.5 | 83.5±8.9 | 0.02 |
| BSA, m2 | 1.67±0.25 | 1.73±0.21 | 1.66±0.23 | 1.65±0.23 | 0.17 |
| Biochemical Data and Cardiometabolic Markers | |||||
| Fasting glucose, mg/dL | 93.3±10.5 | 94.4±9.0 | 98.9±22.1 | 98.1±11 | <0.001 |
| HbA1c, % | 5.62±0.33 | 5.71±0.34 | 5.78±0.54 | 5.88±0.43 | <0.001 |
| Cholesterol, mg/dL | 190.3±33.5 | 189.7±34 | 203.2±37.7 | 200.5±32.6 | <0.001 |
| TG, mg/dL | 131.9±87.4 | 138.3±74.2 | 139.3±104.7 | 131.6±69.8 | 0.52 |
| LDL, mg/dL | 121.5±31 | 125.1±32 | 133.7±33 | 132.4±27.4 | <0.001 |
| HDL, mg/dL | 52.6±13.6 | 50±14 | 53.2±13.8 | 52.1±12.5 | 0.62 |
| Insulin, mIU/mL | 5.4±2.8 | 5.2±3.0 | 5.5±2.4 | 5.3±2.5 | 0.69 |
| HOMA-IR, IU/mL | 1.27±0.63 | 1.28±1.0 | 1.3±0.74 | 1.3±0.8 | 0.82 |
| eGFR, ml.min. 73 m2 | 93.7±16.8 | 90±15.8 | 90.2±15.8 | 85.2±15.8 | <0.001 |
| Lifestyle risk factors | |||||
| Smoking, % | 39 (23.5%) | 36 (25.7%) | 38 (22%) | 28 (21.7%) | 0.846 |
| Exercise, % | 42 (25.3%) | 37 (26.4%) | 48 (27.8%) | 28 (21.7%) | 0.681 |
| Alcohol use, % | 23 (13.9%) | 24 (17.1%) | 51 (29.5%) | 19 (14.7%) | 0.001 |
BMI: body mass index; BSA: body surface area; DBP: diastolic blood pressure; eGFR: estimated glomerular filtration rate; HbA1c: glycosylated hemoglobin level; HDL: high-density lipoprotein; HOMA-IR: homeostasis model assessment-estimated insulin resistance; LDL: low-density lipoprotein; SBP: systolic blood pressure; TG: Triglycerides.