Table 2. General characteristics of the population and experimental conditions during protocol 1 and protocol 2.
| Population (n = 15) | |||
| Age (years) | 32±5 | ||
| Men (%) | 9 (60%) | ||
| BMI (kg/m2) | 22.41±3.76 | ||
| Smoker (%) | 1 (7%) | ||
| During protocol 1 (single current stimulation) | |||
| D1 | D7 | P | |
| Systolic blood pressure (mmHg) | 111±10 | 117±11 | NS |
| Diastolic blood pressure (mmHg) | 70±7 | 72±6 | NS |
| Heart rate (bpm) | 62±10 | 62±11 | NS |
| Skin temperature (°C) | 32.9±1.4 | 33.3±1.1 | NS |
| Laser head distance to skin (cm) | 15.4±0.5 | 15.2±0.4 | NS |
| During protocol 2 (multiple current stimulations) | |||
| D1 | D7 | P | |
| Systolic blood pressure (mmHg) | 119±9 | 116±8 | NS |
| Diastolic blood pressure (mmHg) | 68±7 | 72±5 | NS |
| Heart rate (bpm) | 62±10 | 62±9 | NS |
| Skin temperature (°C) | 32.7±1.6 | 32.0±2.0 | NS |
| Laser head distance to skin (cm) | 15.4±0.3 | 15.4±0.6 | NS |
BMI means Body mass index; bpm means beat per minute. Protocol 1 corresponds to ACh iontophoresis with a single current stimulation (0.1 mA, 30 s). Protocol 2 corresponds to ACh iontophoresis with a multiple current stimulations (four stimulations of 0.1 mA, 10 s with a 2 minute free interval). Protocol 1 and 2 were performed on separated days. Laser head distance was the distance between the laser speckle head and the skin. P means p value. NS means non significant.